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SA antibody breakthrough ‘brings HIV vaccine closer’

SouthAfrican scientists have discovered how some people can make potent antibodies capable of neutralising strains of HIV, taking researchers a step closer to developing a vaccine.

Published
23 October 2012
From
Business Day
HPV vaccination does not lead to an increase in sex

A study published in Vaccine reveals that contrary to recent discussions, the HPV vaccination does not increase sexual activity in adolescent girls.

Published
11 October 2012
From
Eurekalert Medicine & Health
In heterosexuals, transmitted HIV strains often resemble original infecting virus

A new study has found that even though HIV diversifies widely within infected individuals over time, the virus strains that ultimately are passed on through heterosexual transmission often resemble the strain of virus that originally infected the transmitting partner. Learning the characteristics of these preferentially transmitted HIV strains may help advance HIV prevention efforts, particularly with regard to an HIV vaccine, according to the scientists who conducted the study.

Published
25 September 2012
From
Eurekalert Inf Dis
Finding an AIDS Vaccine in the Context of Combination Prevention

“We recognize that suppressive treatment of HIV infection drastically reduces the probability of onward HIV transmission, which should eventually slow the spread of HIV. But the urgent and widespread treatment of HIV is not a substitute for a preventive vaccine. We need an HIV vaccine.”

Published
20 September 2012
From
UNAIDS
AIDS Vaccine Sleuths Find New Clues as 30-Year Hunt Continues

AIDS researchers found clues that help explain why an HIV vaccine worked better for some people than others in a study, advancing scientists’ understanding of the virus.

Published
11 September 2012
From
Bloomberg
RV144 vaccine efficacy increased against certain HIV viruses

Scientists used genetic sequencing to discover new evidence that the first vaccine shown to prevent HIV infection in people also affected the viruses in those who did become infected. Viruses with two genetic "footprints" were associated with greater vaccine efficacy. The results were published today in the online edition of the journal Nature.

Published
10 September 2012
From
Eurekalert Inf Dis
Why an AIDS vaccine has been so difficult to develop

New research explains a decades-old mystery as to why slightly weakened versions of the monkey AIDS virus were able to prevent subsequent infection with the fully virulent strain, but were too risky for human use, and why severely compromised or completely inactivated versions of the virus were not effective at all.

Published
10 September 2012
From
Science Daily
Drug improves vaccine response in HIV patients

The drug maraviroc could help some vaccines work more effectively in people with HIV infection.

Published
24 August 2012
From
Imperial College London press release.
Low levels of innate immune activation and high levels of gut antibodies may protect people from HIV

Several research papers published in the last month have reported strong correlations between specific immune responses and protection against HIV infection or its effects. These include

Published
24 August 2012
By
Gus Cairns
First universal HIV vaccine could be on its way, say researchers

The first effective universal HIV vaccine may soon be on its way thanks to a family of highly potent antibodies which neutralise the virus, according to new findings. Thanks to a group of antibodies named PG and PGTs – isolated from a small group of HIV-infected people – the team believe they are one step closer to creating a one-size-fits all vaccine.

Published
23 August 2012
From
In-PharmaTechnologist.com

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